Jo Cameron, a 71-year-old Scottish woman, has never felt pain all her life, even when giving birth.
According to the New York Times, like many other women, Ms. Cameron was told that childbirth would be very painful. But after a few hours of labor, she still had no problems – even without painkillers.
“I can feel my body change, but it doesn’t hurt,” Mrs. Cameron recalls. She said it was more like someone “tickling” her. Later, she told future moms: “Don’t be too worried, not as bad as everyone says.”
Only recently, after more than four decades – she found that her friends did not exaggerate the pain of pregnancy. The difference is that Mrs. Cameron’s body does not experience pain.
Scientists now believe they have found a reason. In a post in the British Journal of Anesthesia on Thursday (March 28), researchers concluded that life without knowing Cameron’s pain was due to a mutation phenomenon of a Genes that have not been previously identified. Researchers also believe that this mutation is also linked to Mrs. Cameron’s seldom feeling fear or anxiety throughout her life, and that her body heals very quickly.
“We have never met a similar patient,” said John Wood, head of pain research at University College London.
The developments led to Cameron’s genetic research scientists starting about five years ago. At that time, Mrs. Cameron was living a normal and happy life with her husband on the side of Loch Ness, Scotland. After a hand surgery, a doctor found it very strange that she did not feel pain and did not want pain medicine.
“I assure you I don’t need any medicine,” Mrs. Cameron recalled, saying so to Dr. Devjit Srivastava, an expert on anesthesia and painkillers at the Northern Scotland National Hospital.
The next few questions revealed to this doctor that Mrs. Cameron was not normal. At age 65, she had to have a hip replacement surgery. Since there was no pain before, Mrs. Cameron did not find out anything was wrong until her bones were severely degraded. The cuts, burns or reefs – are not painful. Often, it is when the smell of burnt tissue is present or when her husband sees blood flow, she discovers that she is injured. She also ate the most chilli peppers without any problems.
After a few years, the team discovered a gene they called “Faah-out”. We all have this gene. However, in the case of Cameron, she had a dead end at the beginning of the gene sequence. Tests have confirmed this.
A big problem of “not knowing pain” is that Mrs. Cameron does not have the instinct to protect herself from injury.
Scientists are also surprised with her record low level of fear. In a series of questions to diagnose anxiety disorders, she scored 0 points out of 21. She said she never felt depressed or scared.
“I’m very happy,” said Mrs. Cameron.
Scientists have recorded individual cases or felt very little pain during nearly 100 years. But the genetic mutation that led to Mrs. Cameron’s painless life has never been confirmed before.
Researchers hope that this finding could contribute to finding an unprecedented new pain treatment.
This study appears among a series of new developments in a heated debate about how to safely treat pain. On March 28, the State of New York, USA opened one of the biggest lawsuits in history when filing a lawsuit against the Sackler family, owners of the Purdue Pharma pharmaceutical collective, the manufacturer of reducing drugs. OxyCotin pain. This category is responsible for one of the worst addiction crisis in American history.
This case is also a reminder that we need less addictive solutions for the treatment of chronic pain, said neuroscientist at Yale University, Stephen Waxman. Dr. Waxman has studied many patients with rare gene mutations, changing their feelings about pain.
“Each of these mutations gives us new things, and points to genes that can be the basis for developing new pain medications more effectively,” said Dr. Waxman.